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Ȩ Ȩ > ¿¬±¸¹®Çå > ±¹³» ³í¹®Áö > Çѱ¹Á¤º¸Åë½ÅÇÐȸ ³í¹®Áö (Journal of the Korea Institute of Information and Communication Engineering)

Çѱ¹Á¤º¸Åë½ÅÇÐȸ ³í¹®Áö (Journal of the Korea Institute of Information and Communication Engineering)

Current Result Document :

ÇѱÛÁ¦¸ñ(Korean Title) ¸¶ÀÌÅ©·Î¾î·¹ÀÌ ¹ßÇö µ¥ÀÌÅÍ ºÐ·ù¸¦ À§ÇÑ º£ÀÌÁö¾È °ËÁõ ±â¹ý
¿µ¹®Á¦¸ñ(English Title) A Bayesian Validation Method for Classification of Microarray Expression Data
ÀúÀÚ(Author) ¹Ú¼ö¿µ   Á¤Á¾ÇÊ   Á¤Ã¤¿µ   Su-Young Park   Jong-Pil Jung   Chai-Yeoung Jung  
¿ø¹®¼ö·Ïó(Citation) VOL 10 NO. 11 PP. 2039 ~ 2044 (2006. 11)
Çѱ۳»¿ë
(Korean Abstract)
»ý¹°Á¤º¸´Â »ç¶÷ÀÇ ´É·ÂÀ» ³Ñ¾î ¼¹À¸¸ç µ¥ÀÌÅÍ ¸¶ÀÌ´×°ú °°Àº ÀΰøÁö´É±â¹ýÀÌ ÇʼöÀûÀ¸·Î ¿ä±¸µÈ´Ù. ÇÑ ¹ø¿¡ ¼öõ °³ÀÇ À¯ÀüÀÚ ¹ßÇö Á¤º¸¸¦ ȹµæÇÒ ¼ö ÀÖ´Â DNA ¸¶ÀÌÅ©·Î¾î·¹ÀÌ ±â¼úÀº ´ë·®ÀÇ »ý¹°Á¤º¸¸¦ °¡Áø ´ëÇ¥ÀûÀÎ ½Å±â¼ú·Î Áúº´ÀÇ Áø´Ü ¹× ¿¹Ãø¿¡ ÀÖ¾î »õ·Î¿î ºÐ¼®¹æ¹ýµé°ú ¿¬°èÇÏ¿© ¸¹Àº ¿¬±¸°¡ ÁøÇà ÁßÀÌ´Ù. ÀÌ·¯ÇÑ »õ·Î¿î ±â¼úµéÀ» ÀÌ¿ëÇÏ¿© À¯ÀüÀÚÀÇ ¸ÞÄ¿´ÏÁòÀ» ±Ô¸íÇÏ´Â °ÍÀº Áúº´ÀÇ Ä¡·á ¹× ½Å¾àÀÇ °³¹ß¿¡ ¸¹Àº µµ¿òÀ» ÁÙ °ÍÀ¸·Î ±â´ë µÈ´Ù. º» ³í¹®¿¡¼­´Â ¸¶ÀÌÅ©·Î¾î·¹ÀÌ ½ÇÇè¿¡¼­ ´Ù¾çÇÑ ¿øÀο¡ ÀÇÇØ ¹ß»ýÇÏ´Â ÀâÀ½(noise)À» ÁÙÀÌ °Å³ª Á¦°ÅÇÏ´Â °úÁ¤ÀΠǥÁØÈ­°úÁ¤À» °ÅÃÄ Ç¥ÁØÈ­ ¹æ¹ýµéÀÇ ¼º´É ºñ±³¸¦ À§ÇØ Æ¯Â¡ ÃßÃâ¹æ¹ýÀÎ º£ÀÌÁö¾È(Bayesian) ¹æ¹ýÀ» ÀÌ¿ëÇÏ¿© ¸¶ÀÌÅ©·Î¾î·¹ÀÌ µ¥ÀÌÅÍÀÇ ºÐ·ù Á¤È®µµ¸¦ ºñ±³ Æò°¡ÇÏ¿© Lowess Ç¥ÁØÈ­ ÈÄ 95.89%·Î ºÐ·ù¼º´ÉÀ» Çâ»ó½Ãų ¼ö ÀÖÀ½À» º¸¿´´Ù.
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(English Abstract)
Since the bio-information now even exceeds the capability of human brain, the techniques of data mining and artificial intelligent are needed to deal with the information in this field. There are many researches about using DNA microarray technique which can obtain information from thousands of genes at once, for developing new methods of analyzing and predicting of diseases. Discovering the mechanisms of unknown genes by using these new method is expecting to develop the new drugs and new curing methods. In this Paper, We tested accuracy on classification of microarray in Bayesian method to compare normalization method's Performance after dividing data in two class that is a feature abstraction method through a normalization process which reduce or remove noise generating in microarray experiment by various factors. And We represented that it improve classification performance in 95.89% after Lowess normalization.
Å°¿öµå(Keyword) microarray expression data   normalization   Bayesian validation method  
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